In recent years, a number of formerly mothballed divisions of the Weapon Plus Program have been reactivated. Among them was Weapon II, the animal experimentation division of Weapon Plus.
Frisby, known at the time simply as ‘subject 67’, was one of three successful test subjects for an experimental treatment intended to increase the cognitive capacity of an individual designed by the scientists at Weapon II. The treatment was so successful, in fact, that the three test subjects engineered their own escape and left the lab where they had been kept in flames.
The three holed up in a library to consider their next moves and expand their knowledge of the world around them, availing themselves of both books and internet connections during off-hours for several months. During this time, while Frisby and subject 68 studied the world, and hatched megalomaniacal plots to take control of it, subject 69, the mink now dubbed Anastasia, abandoned them and their rapidly-swelling egos to seek her future elsewhere.
When the Squirrel, now known as Ender Q. Frisby, and his partner Edward James Moreau, attempted to put their plans into action, a number of problems presented themselves: First, Ego. Moreau and Frisby each considered himself the superior of the other. Second, creative differences. Frisby preferred simple plans executed with a lot of flash, while Moreau preferred convoluted plans executed with a maximum of both precision and class. Third, Frisby accepted that while he may be intellectually superior to all of humanity, he was obviously physically inferior, and the rest of his species was thoroughly inferior in every conceivable fashion. Moreau considered rodents superior and desired to bring the rest of rodentkind up to just below their level and overthrow humanity. Frisby thought this was, in a word, idiotic. The two split, and set out to pursue their own goals.
Unfortunately, neither could leave the other alone. For a solid year and a half, neither one could succeed at anything, because the other kept interfering. It wasn’t until SHIELD dispatched agents to put an end to the property damage their rivalry was causing that Frisby was ultimately captured, while his hated rival Moreau escaped. Seeing the Initiative project as an equally viable way to get the recognition and glory he desired, Frisby cut a deal with SHIELD to work for them publically and furnish them with the patents and blueprints to everything he designed while working for them.
Why should he care about the potential loss of revenue, after all? He has three to seven years left to live, tops. The trio’s intellect was enhanced, not their longevity.
Subject 67: Fox Squirrel, took the name Ender Q. Frisby, Peerless Engineer, especially skilled in the fields of robotics and AI programming. The first time he was Terminator, he had a working schematic for a T-103 drawn up before the movie was halfway over, plus improvements.
Subject 68: Common Sewer Rat, took the name Edward James Moreau. Incredible chemist, with a particular fondness for mind-altering and -controlling drugs, and temporary mutagens. Has a huge boner for overly complicated plans and a flair for the dramatic. Unlike Frisby, he actually wears clothes, with a penchant for Tuxedos, capes, canes, and top hats. Where he gets them is a damn good question, because they’re too well-tailored to be doll clothes.
Subject 69: White Mink, took the name Anastasia, and scoffed at her male companions’ ridiculous mixed-reference names. Quirks and fields of specialty unknown, as she bailed on the two when they initially began their ridiculous plans.