Here’s a random one from issue #359 of Dragon Magazine on page 65.
Left Ear of Vecna
Constant Powers: Spell Resistance 15; Power Residtance 15.
To be used, this artifact must be placed against the left side of the creatures head after its ear has been removed. The ear grants its host a +5 enhancement bonus on all perception skill checks and a +4 resistance bonus against sonic and language dependant spells and spell-like abilities. The host can use the spells blindness/deafness (deafness only) and clairaudience/clairvoyance (clairaudience only) three times each per day. Once per day, the host may use the spell greater shout. The host can also understand all spoken languages (as per the spell tongues) All spells are cast at caster level 20th and all DCs to resist their effects are 25.
Curse: Every month of attachment, the recipient must make a Will Save (DC 25). On a failed save, the recipient temporarily (4d4+4 hours) acts as if charmed by Vecna and acts according to that powers desires, if applicable.
Destruction: Any force, natural or magical, that can inflict 50 points of damage from a single blow, spell, or effect is sufficient to destroy the left ear. In addition, someone using the molars of Vecna can destroy the relic.